RATES OF DAILY MONITORING OF ARTERIAL PRESSURE AND KIDNEYS FUNCTIONING AGAINST THE BACKGROUND OF COMBINED THERAPY BY CORDINORM AND VALZ AT ARTERIAL HYPERTENSION

Savina Ol'ga Valer'evna, Assistant, sub-department of internal diseases, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), pgu-vb2004@mail.ru
Burmistrova Larisa Fedorovna, Candidate of medical sciences, associate professor, sub-department of internal diseases, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), lamax-69@mail.ru
Rakhmatullov Fagim Kasymovich, Doctor of medical sciences, professor, head of sub-department of internal diseases, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), pgu- vb2004@mail.ru
Bibarsova Aliya Mukhamedzhanovna, Candidate of medical sciences, associate professor, sub-department of internal diseases, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), pgu-vb2004@mail.ru
Sisina Ol'ga Nikolaevna, Candidate of medical sciences, head of sub-department nephrology, Penza Institute of Advanced Medical Studies (8a Stasova street, Penza, Russia), olganicolaevna58@bk.ru

616.12-008.331.1.

Background. The purpose of the article is to evaluate the anti-hypertensive and nephroprotective effects and tolerability of combined therapy by β-adrenergic antagonists and antagonists of receptors to angiotensine II in patients with hypertension.
Materials and methods. In this study the authors used the Statement Ambulatory Monitoring of Blood Pressure (SAMBP). The glomerular filtration rate was calculated using the Cockroft-Goult’s equation, microalbuminuria was evaluated by test strips.
Results. It was revealed that the combination of Cordinorm and Valz allows to achieve target levels of blood pressure (BP) in 86 % of cases, improve the daily profile of BP and also show the pronounced nephroprotectiv effect of treatment. The combination of Cordinorm and Valz contributed to a significant reduction in the frequency of side effects of each component by reducing their doses.
Conclusions. The combination of Cordinorm and Valz has improved antihypertensive and nephroprotective performance and good tolerability that allow to recommend this combination for treatment of patients with hypertension.

arterial hypertension, Cordinorm, Valz, renoprotection, microalbuminuria.

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